Prognostic Value of Measuring Load of Human Papillomavirus DNA in Cervical Samples: An Elusive Target
نویسندگان
چکیده
منابع مشابه
Prognostic Value of DNA and mRNA E6/E7 of Human Papillomavirus in the Evolution of Cervical Intraepithelial Neoplasia Grade 2
OBJECTIVE This study aimed at evaluating whether human papillomavirus (HPV) groups and E6/E7 mRNA of HPV 16, 18, 31, 33, and 45 are prognostic of cervical intraepithelial neoplasia (CIN) 2 outcome in women with a cervical smear showing a low-grade squamous intraepithelial lesion (LSIL). METHODS This cohort study included women with biopsy-confirmed CIN 2 who were followed up for 12 months, wi...
متن کاملHuman papillomavirus viral load in cervical intraepithelial neoplasia as a prognostic factor in a Mexican population.
Persistent infection with human papillomavirus (HPV) has been recognized as the main etiological factor of morbimortality in cervical cancer. Several factors have been associated with the development of cervical disease, but viral load has recently been proposed as an indicator of cervical neoplasia. Therefore, a single measurement of viral load could be a suitable biomarker. We examined HPV vi...
متن کاملIndependent prognostic role of human papillomavirus genotype in cervical cancer
BACKGROUND Although the correlation of HPV genotype with cervical precursor lesions and invasive cancer has been confirmed, the role of HPV genotype in cervical cancer prognosis is less conclusive. This study aims to systematically investigate the independent prognostic role of HPV genotype in cervical cancer. METHODS A total of 306 eligible patients provided cervical cell specimens for HPV g...
متن کاملdetection of human papillomavirus 18 in cervical cancer samples using pcr-elisa (diapops)
background and objectives : human papillomavirus (hpv) infection is a major risk factor for adenocarcinoma of the cervix. the high-risk types of the virus such as hpv16 and hpv18, which possess the e6 and e7 oncogenes, are responsible for approximately 50% of all cervical cancers. a rapid, sensitive and specific test has been proposed for detection of hpv to improve cervical cancer screening pr...
متن کاملPnm-17: Cost Effectiveness of Human Papillomavirus Testing in Cervical Cancer Diagnosis
Background: Epidemiological studies are shown robust association between human papillomavirus (HPV) and cervical cancer. From 1990 HPV was known as a necessary but insufficient cause of cervical invasive cancer. The purpose of this study was to evaluate the cost effectiveness of HPV test in cervical cancer screening. Materials and Methods: This is a systematic review article; the newest scienti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 2009
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djn486